In September 2025, more than 900 participants from across regions and sectors – including human, agrifood, animal, plant and environment - joined the global multi-stakeholder consultations organized and hosted by the AMR Multi-Stakeholder Partnership Platform (MSPP) on behalf of the Quadripartite organizations (FAO, the United Nations Environment Programme, the World Health Organization (WHO) and the World Organisation for Animal Health (WOAH)) on the update of the Global Action Plan on AMR (GAP-AMR) and establishment of an Independent Panel on Evidence for Action Against AMR (IPEA).
By engaging voices from human, animal, agrifood, and environmental sectors — involving research and academia, governments, intergovernmental organizations, civil society, financial institutions, philanthropies, and private sector constituencies — the process sought to ensure that future global strategies reflect shared priorities and diverse realities. The IPEA discussions focused on designing a science–policy panel grounded in equity, transparency, and balanced sectoral participation, particularly for low- and middle-income countries. In parallel, the GAP-AMR consultations aimed to gather insights on the current context, priorities and challenges helping to build a solid vision for collective action under a One Health approach.
Establishing the Independent Panel on Evidence for Action against AMR (IPEA)
More than 500 stakeholders participated to the two–day virtual consultations, most of them emphasizing that the Panel’s work must have tangible impact, producing clear, practical outputs — such as periodic global assessments and targeted policy advice — that help governments and institutions prioritize interventions. Stakeholders also called for explicit attention to the importance of data and evidence systems particularly in low- and middle-income countries, where information gaps hinder action. Participants highlighted that the scope of the Panel should be multisectoral and transdisciplinary, encompassing all dimensions of antimicrobial use — one of the primary drivers of resistance.
Stakeholders stressed that IPEA must complement, not duplicate, the work of existing bodies such as the MSPP and the Global Leaders Group (GLG), serving instead as a mechanism that connects evidence generation with decision-making and implementation.
Regarding governance, stakeholders suggested simplifying it and ensuring it remains flexible and fit for purpose.
Stakeholders from the scientific community noted that the current draft should provide a greater role to independent science and ensure various scientific and expertise is presented.
Updating the Global Action Plan on AMR (GAP-AMR)
First adopted by UN Member States in 2015, the Global Action Plan on Antimicrobial Resistance (GAP-AMR) laid the foundation for more than 170 countries to develop their National Action Plans (NAPs) to address AMR. In response to lessons learned and a rapidly evolving AMR landscape, the 2024 UNGA Political Declaration on AMR called on the Quadripartite organizations to update the Plan by 2026.The draft updated GAP-AMR marks a significant evolution from its original version. It integrates the human, animal, agrifood, plant, and environmental sectors, reflecting a One Health approach and greater emphasis on multisectoral collaboration. More than 400 stakeholders participated in the consultations, welcoming the Plan’s inclusive vision and its potential to serve as a comprehensive roadmap for coordinated AMR action at all levels.
Stakeholders expressed broad support for the Plan’s objectives, particularly praising its multisectoral and inclusive spirit. Objectives on global governance (6) and equitable access (5) were highlighted as particularly critical, requiring stronger focus at country level. Participants also stressed the need to reinforce the Plan’s language on sustainable financing, aligning it with commitments from the UNGA Political Declaration and emphasizing domestic resource mobilization for AMR programs.
Towards a coordinated multi-sectoral and multistakeholder response
The MSPP consultations marked a pivotal step in global AMR governance, showing how inclusive, stakeholder-led dialogue can leverage a broad range of relevant perspectives and expertise, ensuring underrepresented groups, community – based organizations and actors from LMICs are heard and are fully part of the global discussions and action, shaping a unified and collective global vision.
Feedback from participants will now guide the Quadripartite’s revisions of the updated GAP-AMR and the founding document of the IPEA. A summary report from both consultations will be prepared and disseminated by the MSPP.